abstract：:A growing body of research suggests that infant feeding practices influence the risk for several chronic diseases of childhood and adolescence. Increased risks for type 1 diabetes, celiac disease, some childhood cancers, and inflammatory bowel disease have been associated with artificial infant feeding and short-term ...

journal_title：Pediatric clinics of North America

authors： Davis MK

更新日期：2001-02-01 00:00:00

abstract：:ADDs can occur as primary genetic disorders or may develop secondary to various other conditions, including infections, trauma, malnutrition, and protein-losing states. Although antibiotics are the first-line therapy for acute infection, using them prophylactically can select for resistant organisms. IM ISG and fresh ...

journal_title：Pediatric clinics of North America

authors： Schwartz SA

更新日期：2000-12-01 00:00:00

abstract：:Approximately half of children sustain some type of dental injury. Management of injuries to the anterior teeth of preschool children is directed toward minimizing potential damage to the developing permanent teeth; therefore, heroic measures to save primary teeth are not indicated. Crown fractures in the permanent de...

journal_title：Pediatric clinics of North America

authors： McTigue DJ

更新日期：2000-10-01 00:00:00

abstract：:Acne is the most common skin disorder affecting adolescents. Although no cure exists for acne, most patients benefit from currently available medications, and most can be managed effectively by their primary care providers. By offering this care, pediatricians can reduce the emotional burden of acne and help to preven...

journal_title：Pediatric clinics of North America

authors： Krowchuk DP

更新日期：2000-08-01 00:00:00

abstract：:Local anesthetics are often extremely useful in the management of acute, chronic, and procedural pain. They have a low therapeutic ratio, so physicians should not exceed established dosing guidelines for a single bolus or long-term infusions. New local anesthetics that promise better safety and longer duration of acti...

journal_title：Pediatric clinics of North America

authors： Wilder RT

更新日期：2000-06-01 00:00:00

abstract：:Vaccines are now available for the prevention of hepatitis A and hepatitis B. In this article, biologics are reviewed with special attention to their use in the pediatric patient. Special attention is paid to issues that developed in 1999. For hepatitis A vaccine, it is the change in US recommendations regarding incre...

journal_title：Pediatric clinics of North America

authors： Malay S,Tizer K,Lutwick LI

更新日期：2000-04-01 00:00:00

abstract：:The threshold of a new century is an opportune time to review advances in the prevention of HIV infection in children. In the United States, progress in the ability to virtually eliminate perinatal HIV transmission that was unthinkable just a few years ago has been achieved. Clinicians providing care to pregnant women...

journal_title：Pediatric clinics of North America

authors： Bulterys M,Fowler MG

更新日期：2000-02-01 00:00:00

abstract：:Over the past decade, much progress has been made in understanding the risk factors and timing of perinatal HIV transmission. Even more impressive have been the successful clinical trials with antiretrovirals, such as ZDV, ZDV-3TC, and nevirapine, that demonstrated significant reductions in the risk for infant infecti...

journal_title：Pediatric clinics of North America

authors： Fowler MG,Simonds RJ,Roongpisuthipong A

更新日期：2000-02-01 00:00:00

abstract：:Ingestion of potentially poisonous agents is a common reason for children to present to an emergency department. The clinician must decide whether gastrointestinal decontamination is indicated for these patients. The controversy over the type of gastrointestinal decontamination is resolving and recent recommendations ...

journal_title：Pediatric clinics of North America

authors： Tenenbein M

更新日期：1999-12-01 00:00:00

abstract：:ADHD is a syndrome that can be treated effectively, safely, and economically with stimulant medications. There is no equal alternative to these agents in short-term treatment of ADHD symptoms. However, many families seek alternatives to stimulants and other drug treatments for a variety of reasons. Alternative approac...

journal_title：Pediatric clinics of North America

authors： Baumgaertel A

更新日期：1999-10-01 00:00:00

abstract：:ADHD is a highly prevalent condition with the core symptoms of functionally impairing limitations in sustained attention and impulsivity/overactivity. Other frequent symptoms include overemotionality or overreactivity, academic underachievement, low self-esteem, and interpersonal difficulties. The assessment for and d...

journal_title：Pediatric clinics of North America

authors： Mercugliano M

更新日期：1999-10-01 00:00:00

abstract：:Despite declines in adolescent pregnancy rates in the past decade, unplanned pregnancies among adolescents remain a significant problem in the United States. Clinicians caring for adolescents can be certain to encounter pregnancy in their patients. This article addresses surveillance and diagnosis for pregnancy in the...

journal_title：Pediatric clinics of North America

authors： Polaneczky M,O'Connor K

更新日期：1999-08-01 00:00:00

abstract：:Breast lesions, including mastalgia; benign proliferative changes; and benign masses, including fibroadenomas, are common in adolescents and young adult women. Breast cancer is rare in women less than 20 years old and uncommon in women less than 30 years old. Discrete masses in women less than 30 years old that do not...

journal_title：Pediatric clinics of North America

authors： Neinstein LS

更新日期：1999-06-01 00:00:00

abstract：:A left-to-right shunt lesions exists when blood from the left atrium, left ventricle, or aorta transits to the right atrium or its tributaries, the right ventricle, or the pulmonary artery. This article discusses: the incidence, types, embryology, clinical presentations, physical examinations, electrocardiographic fea...

journal_title：Pediatric clinics of North America

authors： Driscoll DJ

更新日期：1999-04-01 00:00:00

abstract：:The evaluation of syncopal children or adolescents relies heavily on a thorough, detailed history and physical examination. All syncope associated with exercise or exertion must be considered dangerous. The ECG is mandatory, but other laboratory tests are generally of limited value unless guided by pertinent positives...

journal_title：Pediatric clinics of North America

authors： Lewis DA,Dhala A

更新日期：1999-04-01 00:00:00

abstract：:Referring to specific types of hearing loss as "minimal" or "mild" seems to imply that their effects are equally mild or negligible. A growing body of literature, however, supports the notion that such losses can have a significant impact on the communicative and educational development of young children. Although OME...

journal_title：Pediatric clinics of North America

authors： Tharpe AM,Bess FH

更新日期：1999-02-01 00:00:00

abstract：:This review represents the author's personal style of practice in a new and evolving field, where the standard academic framework is still in its infancy. When there is no prior established practice to follow, good clinical care needs to come from listening very carefully to patients and empirically judging appropriat...

journal_title：Pediatric clinics of North America

authors： Craighill MC

更新日期：1998-12-01 00:00:00

abstract：:Pediatric patients with ostomies are a challenge to health care providers. An ostomy is not without problems. Knowledge of surgical techniques and a commitment to the care and management of the stoma and appliances are needed to prevent and manage complications. Ongoing patient education is paramount for compliance an...

journal_title：Pediatric clinics of North America

authors： Borkowski S

更新日期：1998-12-01 00:00:00

abstract：:This article outlines the use of alternative agents to TCAs and SSRIs. Features of the more commonly used alternative antidepressant agents are outlined. In addition, antidepressant agents that are currently either under development or used in other countries are indicated for completeness because it seems likely that...

journal_title：Pediatric clinics of North America

authors： McConville BJ,Chaney RO,Browne KL,Friedman L,Cottingham E,Nelson D

更新日期：1998-10-01 00:00:00

abstract：:Traumatic injuries represent the most important threat to the health of children in the United States and are the leading cause of death after the first year of life. More than 20,000 children and young adults will die this year as a result of injury. For every child that dies, another 40 will require hospitalization ...

journal_title：Pediatric clinics of North America

authors： Stylianos S

更新日期：1998-08-01 00:00:00

abstract：:Neonatal surgery has reached a high degree of sophistication. We are now entering a new era of widespread screening of the unborn by means of ultrasound, with planned intrauterine, intrapartum, and immediate postpartum interventions. Many pediatric surgical centers are now focusing their investigative efforts on eluci...

journal_title：Pediatric clinics of North America

authors： Jona JZ

更新日期：1998-06-01 00:00:00

abstract：:Selected topics of violence against children and adolescents that occur in countries outside of the United States are discussed. Focus is given to middle-income and low-income countries and emphasis is placed on the epidemiology of this pressing public health problem, particularly on conditions that are peculiar to ch...

journal_title：Pediatric clinics of North America

authors： Forjuoh SN,Zwi AB

更新日期：1998-04-01 00:00:00

abstract：:Research on human resiliency in the face of adversity has gained widespread currency in the study of the developmental outcomes for children exposed to multiple risk factors. This article reviews several of these studies from a multilevel perspective, with a view to documenting their contributions and limitations and ...

journal_title：Pediatric clinics of North America

authors： Edari R,McManus P

更新日期：1998-04-01 00:00:00

abstract：:The formulation of a diagnosis in a child who has neurologic impairment should not (except in extreme circumstances) be made on the basis of a single finding. For example, the presence of delayed milestones, primitive or exaggerated reflexes, abnormal muscle tone, abnormal posture, abnormal neurologic examination, and...

journal_title：Pediatric clinics of North America

authors： Liptak GS

更新日期：1998-02-01 00:00:00

abstract：:Sexual activity is a common practice among young adolescents, placing them at high risk for STDs, many of which have long-term consequences. Early diagnosis and treatment are essential to limit both the consequences and the spread of these infections. The clinician has a responsibility to the adolescent patient to rec...

journal_title：Pediatric clinics of North America

authors： Lappa S,Moscicki AB

更新日期：1997-12-01 00:00:00

abstract：:Pediatric patients presenting with painless scrotal masses can be perplexing because of the long differential diagnosis. A careful plan based on the physical examination and sonogram findings localizes the mass to the testis or an extratesticular location. Sonography distinguishes solid from cystic lesions. Subsequent...

journal_title：Pediatric clinics of North America

authors： Skoog SJ

更新日期：1997-10-01 00:00:00

abstract：:Despite incomplete understanding of the etiology of Hodgkin's disease and its malignant cell of origin, the majority of children and adolescents diagnosed with Hodgkin's disease will be longterm survivors. Staging and treatment for pediatric Hodgkin's disease has evolved over the past 30 years in attempts to reduce la...

journal_title：Pediatric clinics of North America

authors： Hudson MM,Donaldson SS

更新日期：1997-08-01 00:00:00

abstract：:Careful clinical examination remains the primary and most important way of diagnosing developmental dysplasia of the hip (DDH) in newborn infants. Repeated examinations during the first year are important to diagnose DDH subsequent to the newborn period. Sonography can detect cases of clinically silent DDH. Targeting ...

journal_title：Pediatric clinics of North America

authors： Donaldson JS,Feinstein KA

更新日期：1997-06-01 00:00:00

abstract：:Increasing evidence indicates that the circadian timing system is a fundamental hemostatic system that potently influences human behavior and physiology throughout development. Circadian clock function begins during fetal life, and photic regulation of circadian phase is present at birth in primates. After birth, ther...

journal_title：Pediatric clinics of North America

authors： Rivkees SA

更新日期：1997-04-01 00:00:00

abstract：:This article focuses on recent developments that have defined the autoimmune nature of this entity and its genetic basis, especially the crucial roles of aspartic acid at position 57 of the DQ beta chain and arginine at position 52 of the DQ alpha chain of the HLA complex on chromosome 6 in conferring susceptibility; ...

journal_title：Pediatric clinics of North America

authors： Sperling MA

更新日期：1997-04-01 00:00:00

abstract：:Sepsis remains a major clinical problem in children, with a high mortality rate. Recent discoveries have identified the major cytokines involved in sepsis and several anticytokine strategies have been used in clinical trials. Antiendotoxin, anticytokine, and even steroid therapy have been studied in humans, with limit...

journal_title：Pediatric clinics of North America

authors： Anderson MR,Blumer JL

更新日期：1997-02-01 00:00:00

abstract：:Noncompliance with therapy is widespread in children, with potentially important implications in clinical practice and the research setting. Compliance with therapy is a critical element in the success of therapy, that is, for an efficacious medication to be effective, it must be taken. Demonstration of patterns of dr...

journal_title：Pediatric clinics of North America

authors： Matsui DM

更新日期：1997-02-01 00:00:00

abstract：:Laryngotracheal stenosis should be suspected in children with recurrent, prolonged, or atypical croup; a history of endotracheal intubation; or a history of stridor, feeding difficulties, and failure to thrive. Tracheotomy-dependent patients with acquired laryngotracheal stenosis are candidates for surgical interventi...

journal_title：Pediatric clinics of North America

authors： Lesperance MM,Zalzal GH

更新日期：1996-12-01 00:00:00

abstract：:Auricular reconstruction of microtia is available and is extremely satisfying for the patient, family, and care givers. The patient can look forward to a realistic pinna. With current research activity, auricular reconstruction could evolve even further. The pediatrician is an extremely important member of this effort...

journal_title：Pediatric clinics of North America

authors： Eavey RD

更新日期：1996-12-01 00:00:00

abstract：:Pediatric fractures are seen commonly in emergency departments. Pediatricians are usually the first physicians to assess injured children. Pediatricians should be comfortable in evaluating the fracture and interpreting radiographs prior to consulting an orthopedist. An understanding of the differences between pediatri...

journal_title：Pediatric clinics of North America

authors： England SP,Sundberg S

更新日期：1996-10-01 00:00:00

abstract：:Improvements in diagnosis and treatment have increased survival for many children with malignant bone tumors. New molecular genetic discoveries are providing insights into the mechanisms of tumorigenesis and may provide novel therapeutic modalities based on interfering with aberrant transcriptional activation by hybri...

journal_title：Pediatric clinics of North America

authors： Himelstein BP,Dormans JP

更新日期：1996-08-01 00:00:00

abstract：:The safety of the blood supply has increased tremendously in the past decade. Donor screening and improved infectious disease testing of units for transfusion have contributed to the decreased risk of transfusion-transmitted diseases. Reduction of the number of passenger leukocytes from RBC and platelet transfusions d...

journal_title：Pediatric clinics of North America

authors： Manno CS

更新日期：1996-06-01 00:00:00

abstract：:Important first steps have been taken towards establishing how some nutrients interact with genes and affect intestinal adaptation. These mechanisms may be typical of how other nutrients influence cell function and turnover and help to maintain intestinal integrity. The dietary effects of nucleotides on intestinal cel...

journal_title：Pediatric clinics of North America

authors： LeLeiko NS,Walsh MJ

更新日期：1996-04-01 00:00:00

abstract：:The clinical challenge of determining the medical conditions that are associated with obvious symptoms of gastroesophageal reflux and what diagnostic tests are appropriate to define this relationship is substantial. To determine which infants may be suffering from pathologic conditions associated with subtle signs of ...

journal_title：Pediatric clinics of North America

authors： Hillemeier AC

更新日期：1996-02-01 00:00:00

abstract：:Although the benefits of rhGH and r-HuEPO therapy in children with CRF and on dialysis are already significant, further study of these new additions to the therapeutic arsenal remains necessary. Data on the final adult height achieved in patients who receive rhGH are extremely important information that is as yet unav...

journal_title：Pediatric clinics of North America

authors： Warady BA,Jabs K

更新日期：1995-12-01 00:00:00